Author name: Carl Patel

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Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells | Science

Chemical modulation of proteins enables a mechanistic understanding of biology and represents the foundation of most therapeutics. However, despite decades of research, 80% of the human proteome lacks functional ligands. Chemical proteomics has advanced … Source link

Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells | Science Read More »

urlhttps3A2F2Fcalifornia times brightspot.s3.amazonaws.com2F602F7b2Fd21b89c34da3877a7920430e2b602Fdodgers nationals baseball 24981

Yoshinobu Yamamoto's six scoreless innings help Dodgers complete sweep of Nationals

WASHINGTON —  Yoshinobu Yamamoto had his best start in the big leagues Thursday afternoon. It wasn’t difficult to diagnose the reason why. During an inconsistent opening month to the $325-million pitcher’s rookie season, Yamamoto’s fastball command was too often lacking. Touted as his most reliable trait during a sterling career in Japan’s Nippon Professional Baseball league,

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Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules | Science

Tubulin, one of the most abundant cytoskeletal building blocks, has numerous isotypes in metazoans encoded by different conserved genes. Whether these distinct isotypes form cell type– and context-specific microtubule structures is poorly understood. … Source link

Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules | Science Read More »

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Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts | Science

Organisms exhibit extensive variation in ecological niche breadth, from very narrow (specialists) to very broad (generalists). Two general paradigms have been proposed to explain this variation: (i) trade-offs between performance efficiency and breadth … Source link

Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts | Science Read More »

Expandify AI: Transforming Home Improvement Marketing with Artificial Intelligence

Expandify AI: Transforming Home Improvement Marketing with Artificial Intelligence

Revolutionize home improvement marketing with Expandify AI’s cutting-edge artificial intelligence solutions. Elevate your strategy today! April 26, 2024 / LinkDaddy News / – In a world where digital presence is paramount, Expandify AI stands out as a pioneer in home improvement marketing, offering innovative solutions that harness the power of artificial intelligence. With a focus

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